A Rat Model for Oral Mucositis Induced by a Single Administration of 5-Fluorouracil.

DO Hyung KimJungeun ChoiYun-Sung LimHee Jin HuhChang Gun ChoBo Hae Kim

Published in: In vivo (Athens, Greece) (2023)

Single administration of 200 mg/kg of 5-FU combined with a chemical stimulus can lead to an immune-suppressive status, failure of weight gain, and impairment of epithelium regeneration as observed in a CIOM rat model.

Keyphrases

weight gain
body mass index
birth weight
stem cells
radiation induced
weight loss