Signet ring cell component in pretreatment biopsy predicts pathological response to preoperative chemoradiotherapy in rectal cancer.

Xue ChaoZixian WangShixun LuYuhua HuangShengbing ZangPeirong DingHuizhong ZhangJingping Yun

Published in: International journal of clinical oncology (2020)

Our data suggest that the signet ring cell component in pretreatment biopsies may be a potential predictor of tumor response to PCRT in rectal cancer. This suggests patients with clinical complete response are more suitable for a wait-and-watch approach.

Keyphrases

rectal cancer
locally advanced
single cell
cell therapy
patients undergoing
ultrasound guided
machine learning
risk assessment