Age-associated B cells contribute to the pathogenesis of rheumatoid arthritis by inducing activation of fibroblast-like synoviocytes via TNF-α-mediated ERK1/2 and JAK-STAT1 pathways.
Yi QinMing-Long CaiHui-Zhi JinWei HuangChen ZhuAline BozecJingang HuangZhu ChenPublished in: Annals of the rheumatic diseases (2022)
Our results suggest that ABCs contribute to the pathogenesis of RA by inducing the activation of FLS via TNF-α-mediated ERK1/2 and JAK-STAT1 pathways.