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METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N 6 -methyladenosine modification of PD-L1 mRNA in breast cancer.

Weijun WanXiang AoQuan ChenYang YuLuoquan AoWei XingWei GuoXiaofeng WuChengxiu PuXueting HuZhan LiMengwei YaoDonglin LuoXiang Xu
Published in: Molecular cancer (2022)
A-IGF2BP3-dependent manner to further promote stabilization of PD-L1 mRNA, which may have important implications for new and efficient therapeutic strategies in the tumor immunotherapy.
Keyphrases
  • binding protein
  • pi k akt
  • young adults
  • signaling pathway