Cardiac Resident Macrophage-Derived Legumain Improves Cardiac Repair by Promoting Clearance and Degradation of Apoptotic Cardiomyocytes After Myocardial Infarction.
Daile JiaSiqin ChenPei-Yuan BaiChentao LuoJin LiuAi-Jun SunJun-Bo GePublished in: Circulation (2022)
Our results directly link efferocytosis to wound healing in the heart and identify Lgmn as a significant link between acute inflammation resolution and organ function.