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Associations of genetically determined iron status across the phenome: A mendelian randomization study.

Dipender GillBeben BenyaminLuke Stephen Prockter MooreGrace MonoriAng ZhouFotios KoskeridisEvangelos EvangelouMike LaffanAnn P WalkerKonstantinos K TsilidisAbbas DehghanPaul ElliottElina HyppӧnenJoanna Tzoulaki
Published in: PLoS medicine (2019)
Our findings offer novel, to our knowledge, insight into previously unreported effects of iron status, highlighting a potential protective effect of higher iron status on hypercholesterolemia and a detrimental role on risk of skin and skin structure infections. Given the modifiable and variable nature of iron status, these findings warrant further investigation.
Keyphrases
  • iron deficiency
  • soft tissue
  • cardiovascular disease
  • type diabetes
  • wound healing
  • coronary artery disease
  • cardiovascular events
  • risk assessment
  • climate change