Determination of irinotecan, SN-38 and SN-38 glucuronide using HPLC/MS/MS: Application in a clinical pharmacokinetic and personalized medicine in colorectal cancer patients.
Chalirmporn AtasilpPichai ChansriwongEkapob SirachainanThanyanan ReungwetwattanaApichaya PuangpetchSantirhat PrommasSuwannee SirilerttrakulBudsaba RerkarmnuaychokeSansanee WongwaisayawanChonlaphat SukasemPublished in: Journal of clinical laboratory analysis (2017)
This method was successfully used to quantify CPT-11, SN-38, and SN-38G and applied to a pharmacokinetic study.