The comparison of cardiovascular disease risk prediction scores and evaluation of subclinical atherosclerosis in rheumatoid arthritis: a cross-sectional study.
Hafis MuhammedDurga Prasanna MisraNeeraj JainSujata GangulySarit Sekhar PattanaikMohit Kumar RaiAnamika Kumari AnujaNamita MohindraSudeep KumarVikas AgarwalPublished in: Clinical rheumatology (2022)
Individual CVD risk scores predict 10-year CVD risk differently in Indian patients with RA, and require validation for predicting hard end points (CVD events, mortality). Key Points • Diabetes mellitus and hypertension are the most prevalent cardiovascular disease risk factors in Indian patients with RA. • Individual cardiovascular risk prediction scores predict risk differently in Indian patients with RA, highest risk being predicted by the FRS-BMI. • Carotid intima-media thickness in RA associated with increasing age, male sex and extra-articular manifestations. • 14% RA had subclinical atherosclerosis, associated with increasing age, male sex, and higher total cholesterol to HDL-C ratio, best distinguished by ASCVD and QRISK-2 scores.
Keyphrases
- rheumatoid arthritis
- cardiovascular disease
- disease activity
- risk factors
- ankylosing spondylitis
- blood pressure
- systemic lupus erythematosus
- physical activity
- cardiovascular events
- body mass index
- cardiovascular risk factors
- optical coherence tomography
- insulin resistance
- clinical evaluation
- idiopathic pulmonary fibrosis