Satellite cell self-renewal in endurance exercise is mediated by inhibition of mitochondrial oxygen consumption.

Published in: Journal of cachexia, sarcopenia and muscle (2020)

Our results indicate that endurance exercise promotes self-renewal and inhibits differentiation in satellite cells, an effect promoted by metabolic reprogramming and respiratory inhibition, which is associated with a more favourable muscular response to injury.

Keyphrases

resistance training
high intensity
body composition
induced apoptosis
skeletal muscle
physical activity
single cell
oxidative stress
cell cycle arrest
cell therapy
endoplasmic reticulum stress
cell proliferation
signaling pathway
bone marrow