Clozapine-induced myocarditis in children and adolescents: a pharmacovigilance study using VigiBase and a systematic literature review.

Carlos de Las CuevasManuel Arrojo-RomeroCan-Jun RuanGeorgios Schoretsanitis Emílio J Sanz Jose De Leon

Published in: Expert opinion on drug metabolism & toxicology (2022)

These 41 cases of at least possible clozapine-induced myocarditis indicated that this ADR can definitively occur in children, particularly in the first 30 days of up-titration. Children's and adult cases appeared similar.

Keyphrases

high glucose
young adults
diabetic rats
drug induced
adverse drug
endothelial cells
stress induced