Lightly Boron-Doped Nanodiamonds for Quantum Sensing Applications.
Masfer AlkahtaniDmitrii K ZharkovAndrey V LeontyevArtemi G ShmelevVictor G NikiforovPhilip R HemmerPublished in: Nanomaterials (Basel, Switzerland) (2022)
Unlike standard nanodiamonds (NDs), boron-doped nanodiamonds (BNDs) have shown great potential in heating a local environment, such as tumor cells, when excited with NIR lasers (808 nm). This advantage makes BNDs of special interest for hyperthermia and thermoablation therapy. In this study, we demonstrate that the negatively charged color center (NV) in lightly boron-doped nanodiamonds (BNDs) can optically sense small temperature changes when heated with an 800 nm laser even though the correct charge state of the NV is not expected to be as stable in a boron-doped diamond. The reported BNDs can sense temperature changes over the biological temperature range with a sensitivity reaching 250 mK/√Hz. These results suggest that BNDs are promising dual-function bio-probes in hyperthermia or thermoablation therapy as well as other quantum sensing applications, including magnetic sensing.
Keyphrases
- quantum dots
- highly efficient
- photodynamic therapy
- energy transfer
- metal organic framework
- visible light
- molecular dynamics
- fluorescence imaging
- stem cells
- single molecule
- drug delivery
- mass spectrometry
- human health
- living cells
- fluorescent probe
- nucleic acid
- high speed
- simultaneous determination
- replacement therapy
- smoking cessation