Green mediated synthesis of cerium oxide nanoparticles by using Oroxylum indicum for evaluation of catalytic and biomedical activity.

The present perspective emphasizes the green synthesis of CeO 2 -NPs using Oroxylum indicum fruit extract. The synthesized NPs were characterized utilizing analytical techniques, including FT-IR, UV-vis, XRD, SEM-EDX, and VSM. Of them, XRD analysis ratifies the cubic fluorite crystal structure along with a particle size of 23.58 nm. EDX results support the presence of cerium and oxygen in a proper ratio. The surface morphology of NPs, however, was scrutinized using SEM. The lower IC 50 value (20.8 μg mL -1 ) of NPs compared to the reference substance, ascorbic acid (33.2 μg mL -1 ), demonstrates CeO 2 -NPs to be a compatible antioxidant. Moreover, the drug-releasing capability of CeO 2 -NPs was a buffer pH-dependent parameter. The acidic pH solution was 20.5%, while the basic pH solution was 16.9%. The drug-releasing capability was analyzed using the Higuchi model and Korsmeyer-Peppas kinetics. The values of the determination coefficient ( R 2 ) were found to be 0.9944 and 0.9834, respectively. The photocatalytic activity of CeO 2 -NPs was evaluated, considering methylene blue as a model dye. The degradation percentage was attained up to 56.77% after it had been exposed for 150 min. Apart from this, the synthesized NPs were screened against two fungus species, Bipolaris sorokiniana and Fusarium . The percentage of growth was measured at 56% and 49%, respectively.