TRDMT1 exhibited protective effects against LPS-induced inflammation in rats through TLR4-NF-κB/MAPK-TNF-α pathway.

Zhengguang LiXiaolong QiXu ZhangLei YuLijuan GaoWeining KongWei ChenWei DongLijun LuoDan LuLianfeng Zhang Yuanwu Ma

Published in: Animal models and experimental medicine (2022)

Our data demonstrated that Trdmt1 plays a protective role in inflammation by regulating the TLR4-NF-κB/MAPK-TNF-α pathway. This work provides useful information to understand the TRDMT1 function in inflammation.

Keyphrases

lps induced
oxidative stress
inflammatory response
signaling pathway
toll like receptor
pi k akt
rheumatoid arthritis
nuclear factor
immune response
healthcare
electronic health record
social media
data analysis