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Role of MicroRNA-124 as a Prognostic Factor in Multiple Neoplasms: A Meta-Analysis.

Zijian ZhouJiancheng LvJingzi WangHao YuHongcheng LuBaorui YuanJie HanRui ZhouXiaolei ZhangXiao YangHaiwei YangQiang LuPengchao Li
Published in: Disease markers (2019)
Taken together, our results suggest that miR-124 plays an antioncogenic role in various tumors, such as lung cancer and colorectal cancer. If methylation of miR-124 could be prevented, progression and metastasis would be improved; thus, miR-124 may be a promising biomarker and novel therapeutic target. Further large-scale studies are needed to confirm this possible effect.
Keyphrases
  • cell proliferation
  • long non coding rna
  • prognostic factors
  • long noncoding rna
  • dna methylation
  • case control