PD-L1 and PD-L2 expression correlated genes in non-small-cell lung cancer.

Trine Vilsbøll LarsenDianna HussmannAnders Lade Nielsen

Published in: Cancer communications (London, England) (2019)

We present gene signatures associated with PD-L1 and PD-L2 mRNA expression in NSCLC which could possess importance in relation to understand PD-1 checkpoint blockade-responsive biology and development of gene signature based biomarkers for predicting clinical responses to immunotherapy.

Keyphrases

genome wide
genome wide identification
copy number
small cell lung cancer
dna methylation
dna damage
genome wide analysis
cell cycle
transcription factor
cancer therapy
advanced non small cell lung cancer
gene expression
drug delivery
cell proliferation
oxidative stress
bioinformatics analysis