Prevalence and Some Possible Mechanisms of Colistin Resistance Among Multidrug-Resistant and Extensively Drug-Resistant Pseudomonas aeruginosa.

Rehab Mahmoud Abd El-BakySalwa M MasoudDoaa S MohamedNancy Gfm WalyEngy A ShafikDina A MoharebAzza ElkadyMohamed M ElbadrHelal F Hetta

Published in: Infection and drug resistance (2020)

The current study reports a high prevalence of colistin resistance and mcr-1 gene in P. aeruginosa strains isolated from Egypt that may result in untreatable infections. Our finding makes it urgent to avoid unnecessary clinical use of colistin.

Keyphrases

multidrug resistant
drug resistant
acinetobacter baumannii
gram negative
klebsiella pneumoniae
pseudomonas aeruginosa
escherichia coli
risk factors
cystic fibrosis
copy number
genome wide
biofilm formation
emergency department
dna methylation
gene expression
electronic health record
adverse drug