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Nasal epithelial cell culture fluorescence recovery after photobleaching predicts cystic fibrosis therapeutic response.

Timothy E CorcoranCarol A BertrandMichael M MyerburgDaniel J WeinerSheila A FrizzellAnna LiBrittani AgostiniRobert S ParkerMonica E ShapiroAshok MuthukrishnanNicholas D HagesBrian P MulhernJoseph M Pilewski
Published in: ERJ open research (2022)
measurements of FRAP were particularly useful for predicting response and for characterising important properties of ASL mucus that were ultimately reflected in lung physiology.
Keyphrases
  • cystic fibrosis
  • pseudomonas aeruginosa
  • lung function
  • chronic obstructive pulmonary disease
  • air pollution
  • chronic rhinosinusitis