Genomic analysis of focal nodular hyperplasia with associated hepatocellular carcinoma unveils its malignant potential: a case report.
Caner ErcanMairene Coto-LlerenaJohn GallonLana FourieMattia MarinucciGabriel Fridolin HessJürg VosbeckStephanie Taha-MehlitzTuyana BoldanovaMarie-Anne MeierAlexandar TzankovMatthias S MatterMartin H K HoffmannLuca Di TommasoMarkus von FlüeCharlotte C K NgMarkus H HeimSavas D SoysalLuigi M TerraccianoOtto KollmarSalvatore PiscuoglioPublished in: Communications medicine (2022)
To the best of our knowledge, our work is the first study showing a clonal relationship between FNH and HCC. We show that FNH may possess the capability to undergo malignant transformation and to progress to HCC in very rare cases.
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