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Extended application of the rapid post-mortem test kit for bovine spongiform encephalopathy to chronic wasting disease.

Yuichi MatsuuraKohtaro MiyazawaMotohiro HoriuchiAkio SuzukiMayumi YokoyamaMorikazu ImamuraKeigo IkedaYoshifumi Iwamaru
Published in: Microbiology and immunology (2022)
Chronic wasting disease (CWD) is a prion disease affecting cervid species primarily in the United States of America and Canada; however, it is now emerging in Scandinavian countries. Although CWD cases have not been reported in Japan, in case of a CWD outbreak occuring, it is critical to prepare for testing a large number of specimens. The present study showed that a rapid post-mortem test kit, which is used for bovine spongiform encephalopathy surveillance in Japan, is valid for the detection of CWD prion.
Keyphrases
  • loop mediated isothermal amplification
  • early onset
  • public health
  • label free
  • real time pcr
  • genetic diversity