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Proteome profiling of human placenta reveals developmental stage-dependent alterations in protein signature.

Sara Khorami SarvestaniSorour ShojaeianNegar VanakiBehrouz Ghresi-FardMehdi AminiKambiz GilanyHale SoltanghoraeeSoheila ArefiMahmood Jeddi-TehraniAmir Hassan Zarnani
Published in: Clinical proteomics (2021)
According to Reactome and PANTHER softwares, these proteins were mostly involved in response to chemical stimulus and stress, regulation of biological quality, programmed cell death, hemostatic and catabolic processes, protein folding, cellular oxidant detoxification, coagulation and retina homeostasis. Elucidation of alteration in protein signature during placental development would provide researchers with a better understanding of the critical biological processes of placentogenesis and delineate proteins involved in regulation of placental function during development.
Keyphrases
  • protein protein
  • endothelial cells
  • amino acid
  • binding protein
  • single cell
  • small molecule
  • stress induced