Effect of age on the cardiovascular remodelling induced by chronic intermittent hypoxia as a murine model of sleep apnoea.

Anabel Lourdes Castro-GrattoniMonique Suarez-GironIvan BenitezMarta TorresIsaac AlmendrosRamon FarreJosep M MontserratMireia DalmasesDavid GozalManuel Sánchez-de-la-Torrenull null

Published in: Respirology (Carlton, Vic.) (2019)

Cardiovascular remodelling induced by severe CIH is affected by the age at which CIH onset occurs, suggesting that the deleterious cardiovascular effects associated with CIH may be more pronounced in younger populations, and such changes resemble chronological age-related declines in cardiovascular structural integrity.

Keyphrases

physical activity
early onset
drug induced
positive airway pressure
genetic diversity