Bone mineral density among children living with HIV failing first-line anti-retroviral therapy in Uganda: A sub-study of the CHAPAS-4 trial.
Eva NatukundaAlex SzubertCaroline OtikeImerida NamyaloEsther NambiAlasdair BamfordKatja DoerholtDiana M GibbVictor MusiimePhillipa MusokePublished in: PloS one (2023)
Nearly 20% CLWH failing first-line ART had low BMD which was associated with female sex, older age, first-line ZDV exposure, and low BMI. Prevention, monitoring, and implications following transition to adult care should be prioritized to identify poor bone health in HIV+adolescents entering adulthood.
Keyphrases
- bone mineral density
- postmenopausal women
- young adults
- healthcare
- body composition
- antiretroviral therapy
- hiv infected
- physical activity
- hiv positive
- public health
- human immunodeficiency virus
- hepatitis c virus
- palliative care
- hiv aids
- clinical trial
- study protocol
- depressive symptoms
- mental health
- phase ii
- stem cells
- childhood cancer
- health promotion
- men who have sex with men
- pain management
- chronic pain
- mesenchymal stem cells
- south africa
- weight loss
- human health
- bone loss