Combined intermittent and sustained hypoxia is a novel and deleterious cardio-metabolic phenotype.
Xin ZhenEsteban A MoyaMary GautaneHuayi ZhaoElijah S LawrenceWanjun GuLaura A BarnesJason X-J YuanPritesh P JainMingmei XiongPablo Catalan SerraLuu V PhamAtul MalhotraTatum S SimonsonOmar A MesarwiPublished in: Sleep (2021)
Overlap hypoxia may represent a unique and deleterious cardio-metabolic stimulus, causing systemic and pulmonary hypertension, and without protective metabolic effects characteristic of sustained hypoxia.