Impact of germline mutations in cancer-predisposing genes on long-term survival in patients with epithelial ovarian cancer.
Joanne KotsopoulosNeda ZamaniBarry RosenJohn R McLaughlinHarvey A RischShana J KimPing SunMohammad Reza AkbariSteven A NarodPublished in: British journal of cancer (2022)
The most important predictor of long-term survival was no residual disease post surgery. BRCA mutation status was not predictive of long-term survival while those with MMR mutations had excellent survival. Larger studies on PALB2 carriers are needed.