Retrospective cohort study of the efficacy and safety of dabigatran: real-life dabigatran use including very low-dose 75 mg twice daily administration.
Yuuki AkagiTatsuo ChibaShusuke UekusaHiroyoshi KatoShigeo YamamuraYukiko AokiMizuho EnokiYuka OgawaraTakanori KasaharaYuki KimuraTadahiro ShimizuAiko TakeishiYuko NakajimaHideki KobayashiKaoru SugiPublished in: Journal of pharmaceutical health care and sciences (2019)
The results suggest that sufficient anticoagulation efficacy may not be maintained when the dabigatran dose is excessively reduced to 75 mg twice daily.