Secondary Palate Development in the Dog (Canis lupus familiaris).
Katharina FreibergerShelby HemkerRyan McAnallyRachel KingVicki N Meyers-WallenBrian C SchutteJohn C FyfePublished in: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association (2020)
Palate development occurs in dogs in the steps described in humans and mice, but palate closure occurs at an intermediate time in gestation. These normative data will form the basis of future studies to determine pathophysiologic mechanisms in dog models of CP. Added clinical significance is the enhancement of dogs as a large animal model to test new approaches for palate repair, with the obvious advantage of achieving full maturity within 2 years rather than 2 decades.