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Single-cell transcriptome profiling reveals the key role of ZNF683 in natural killer cell exhaustion in multiple myeloma.

Xin LiMengping ChenYike WanLu ZhongXiaofeng HanXiaotong ChenFei XiaoJia LiuYiwei ZhangDi ZhuJing XiangJunling LiuHonghui HuangJian Hou
Published in: Clinical and translational medicine (2022)
NK cell exhaustion and suggest that transcriptional suppressor ZNF683 as a potential useful therapeutic target in immunotherapy of MM.
Keyphrases
  • single cell
  • nk cells
  • rna seq
  • multiple myeloma
  • high throughput
  • gene expression
  • transcription factor
  • stem cells
  • human health
  • genome wide
  • heat shock
  • risk assessment
  • climate change
  • mesenchymal stem cells
  • bone marrow