Late recurrence of chromophobe renal cell carcinoma to unusual sites after 12 years of radical nephrectomy and radiotherapy: a rare case report from Syria.
Jaafar ZahloutHaidar ShmayyesBatoul ZahloutMariam SalloumYahya KassabNadim ZahloukZuheir AlshehabiPublished in: Annals of medicine and surgery (2012) (2023)
We reported evidence for the potential of a relatively indolent histologic type of RCC (i.e. chromophobe cell carcinoma) to cause late recurrence after 12 years to a very rare site (i.e. abdominal wall's superficial muscles). Research should focus on addressing late recurrence to determine the best surveillance protocols; investigating malignant cells seeding during surgery to improve surgical oncology's outcomes; and studying late recurrence's genetics to boost our targeted therapy options.
Keyphrases
- renal cell carcinoma
- rare case
- free survival
- minimally invasive
- induced apoptosis
- palliative care
- public health
- early stage
- radiation therapy
- adipose tissue
- cell cycle arrest
- metabolic syndrome
- coronary artery disease
- signaling pathway
- cell proliferation
- endoplasmic reticulum stress
- percutaneous coronary intervention
- oxidative stress
- atrial fibrillation