Anti-biofilm activity of murepavadin against cystic fibrosis Pseudomonas aeruginosa isolates.

María Díez-AguilarMiquel EkkelenkampMaría-Isabel MorosiniNatalia HuertasRosa Del CampoJavier ZamoraAd C FluitMichael M TunneyDaniel ObrechtFrancesca BernardiniRafael Cantón

Published in: The Journal of antimicrobial chemotherapy (2021)

Murepavadin demonstrated good activity against P. aeruginosa biofilms both in open and closed systems. The MBIC-ECOFF and the MBEC-ECOFF are proposed as new parameters to estimate the activity of antibiotics on biofilms.

Keyphrases

pseudomonas aeruginosa
cystic fibrosis
candida albicans
biofilm formation
staphylococcus aureus
minimally invasive
lung function
chronic obstructive pulmonary disease
drug resistant
multidrug resistant