Chemokine receptor 7 mediates miRNA-182 to regulate cerebral ischemia/reperfusion injury in rats.

Qi WangSifan XuBin WangYu QinYachen JiQian YangYang XuZhiming Zhou

Published in: CNS neuroscience & therapeutics (2022)

CXCR7 protects against cerebral I/R injury, possibly via the miR-182/TCF7L2/Hippo pathway. These results indicate that CXCR7 affects cerebral ischemia-reperfusion injury through miRNA regulation and downstream pathways.

Keyphrases

subarachnoid hemorrhage
ischemia reperfusion injury
cell proliferation
cerebral ischemia
long non coding rna
cell migration
cerebral blood flow
long noncoding rna
binding protein