Juvenile polyposis syndrome with gastric and duodenal polyposis presenting with refractory anemia and protein-leakage gastroenteropathy in a patient with SMAD4 mutation: a case report.
Kenya NakamuraKoji KubotaAkira ShimizuTsuyoshi NotakeTomohiko IkeharaKentaro UmemuraAtsushi KamachiTakamune GotoHidenori TomidaYoshiyuki TakahashiTadanobu NagayaTakeji UmemuraYuji SoejimaPublished in: Surgical case reports (2024)
We report a case of JPS with refractory anemia and protein-losing gastroenteropathy that was treated with total gastrectomy with concomitant pancreaticoduodenectomy. Although the surgery was highly invasive, the patient's nutritional status and anemia improved postoperatively, and the treatment was successful. However, to determine the appropriate surgical procedure, a detailed examination of the gastrointestinal lesions and the effects of the surgical invasion on nutritional status must be undertaken.
Keyphrases
- case report
- iron deficiency
- chronic kidney disease
- minimally invasive
- protein protein
- epithelial mesenchymal transition
- coronary artery bypass
- binding protein
- transforming growth factor
- coronary artery disease
- cell migration
- small molecule
- acute coronary syndrome
- signaling pathway
- newly diagnosed
- smoking cessation