Endoplasmic Reticulum Protein 72 Regulates Integrin Mac-1 Activity to Influence Neutrophil Recruitment.

Yaofeng LiXulin XuHaoqing Jerry WangYiyao Catherine ChenYaobing ChenJoyce Chiu Li LiLei WangJinyu WangZhaoming Tang Lehao Ren Hongliang Li Xuan-Bin Wang Si JinYi WuMingdong HuangLining Arnold Arnold Ju Chao Fang

Published in: Arteriosclerosis, thrombosis, and vascular biology (2024)

Extracellular ERp72 regulates integrin Mac-1 activity by catalyzing disulfide rearrangement on the αM subunit and may be a novel target for the treatment of neutrophil-associated vasculopathy.

Keyphrases

endoplasmic reticulum
cell migration
cell adhesion
small molecule
amino acid
binding protein