Association of Pathology Markers with Somatostatin Analogue Responsiveness in Acromegaly.
George KontogeorgosVyron MarkussisEleni ThodouEfi KyrodimouTheodossia ChoreftakiPanagiotis NomikosKostas I LampropoulosStylianos TsagarakisPublished in: International journal of endocrinology (2022)
The novel marker ZAC-1 was associated with GH response to medical treatment with SS-a. The SGSA cases were characterized by higher Ki-67 values and MR T2 signals indicative of an inferior response to SS-a. These findings improve our understanding of the mechanisms underlying SA response to medical treatment.