Association of Medication Adherence and Health Status in Heart Failure With Reduced Ejection Fraction: Insights From the CHAMP-HF Registry.
Rayan S El-ZeinMoghniuddin MohammedDaniel D NguyenC Larry HillLaine ThomasMichael NassifAdam D DeVoreNancy M AlbertJaved ButlerJ Herbert PattersonFredonia B WilliamsAdrian F HernandezGregory Y H LipJohn A SpertusPublished in: Circulation. Cardiovascular quality and outcomes (2024)
In HFrEF, medication nonadherence was associated with worse health status and less improvement over the following year. Improvements in adherence were associated with better health status than remaining nonadherent, underscoring the importance of supporting adherence with guideline-directed medical therapy in patients with HFrEF.