Cancer-stromal cell fusion as revealed by fluorescence protein tracking.
Ruoxiang WangMichael S LewisJi LyuHaiyen E ZhauStephen J PandolLeland W K ChungPublished in: The Prostate (2019)
Cancer-stromal cell fusion leads to cancer cell heterogeneity. The cancer-stromal coculture system characterized in this study can be used as a model for molecular characterization of cancer cell fusion as the mechanism behind the progression of heterogeneity observed in clinical prostate cancers.