Genome-wide transcriptome study using deep RNA sequencing for myocardial infarction and coronary artery calcification.

Xiaoling ZhangJeroen G J van RooijYoshiyuki WakabayashiShih-Jen HwangYanqin YangMohsen GhanbariDaniel Bosnull nullDaniel LevyAndrew D JohnsonJoyce B J van MeursMaryam KavousiJun ZhuChristopher J O'Donnell

Published in: BMC medical genomics (2021)

We identified transcriptomic signatures of early MI that include differentially expressed protein-coding genes and lincRNAs, suggesting important roles for protein-coding genes and lincRNAs in the pathogenesis of MI.

Keyphrases

genome wide
dna methylation
coronary artery
single cell
copy number
rna seq
heart failure
pulmonary artery
amino acid
chronic kidney disease
left ventricular
binding protein
gene expression
bioinformatics analysis
pulmonary hypertension