Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs.

Kateřina HanákováOndřej BernatíkMarek KravecMiroslav MickaJitender KumarJakub HarnošPetra OvesnáPetra PaclíkováMatěj RádsetoulalDavid PotěšilKonstantinos TripsianesLukáš ČajánekZbyněk ZdráhalVitezslav Bryja

Published in: Cell communication and signaling : CCS (2019)

We identify unique phosphorylation barcodes associated with DVL function. Our data provide an example of functional synergy between phosphorylation in structured domains and unstructured IDRs that together dictate the biological outcome. Video Abtract.

Keyphrases

protein kinase
electronic health record
big data
gene expression