A Multicomponent Approach toward Angularly Fused/Linear Bitriazoles: A Cascade Cornforth Rearrangement and Triazolization.

A multicomponent reaction of triazoloketones, primary amines, and 4-nitrophenyl azide was developed for the synthesis of hitherto unknown angularly fused/linear bitriazoles. The two-stage mechanism was well proven by the isolation of the intermediate. This sequential reaction consists of Cornforth rearrangement and triazolization, which has also been demonstrated in a one-pot manner.