Urinary TIMP-2*IGFBP-7 to diagnose acute kidney injury in children receiving cisplatin.
Hayton ChuiKelly R McMahonShahrad Rod RassekhKirk R SchultzTom D Blydt-HansenCherry MammenMaury PinskGeoffrey D E CuvelierBruce C CarletonRoss T TsuyukiColin J D RossPrasad DevarajanLouis HuynhMariya YordanovaFrédérik Crépeau-HubertStella WangVedran CockovskiAna PalijanMichael Zappitellinull nullPublished in: Pediatric nephrology (Berlin, Germany) (2023)
TIMP-2*IGFBP-7 were poor to modest at detecting AKI post-cisplatin. Additional studies are needed to determine whether raw biomarker values or biomarker values normalized to urinary creatinine are more strongly associated with patient outcomes. A higher resolution version of the Graphical abstract is available as Supplementary information.