Albizzia chinensis (Osbeck) Merr extract YS ameliorates ethanol-induced acute gastric ulcer injury in rats by regulating NRF2 signaling pathway.

Bo TangLiangning LiYuanzhi YuGuibin WangShuanggang MaShishan YuJianjun Zhang

Published in: Animal models and experimental medicine (2024)

YS reduced the NRF2-Keap1 interaction, promoting NRF2 translocation into the nucleus, which increasing the transcription and translation of NQO1 and HO-1 and improved the antioxidant capacity of rat stomach.

Keyphrases

oxidative stress
signaling pathway
pi k akt
induced apoptosis
transcription factor
epithelial mesenchymal transition
cell proliferation
anti inflammatory