Human Umbilical Cord Wharton Jelly Cells Treatment Prevents Osteoporosis Induced by D-Galactose.
Qiang WangZhiqiang GaoKai GuoJiawei LuFeng WangTongde WuYu-Feng HuangDesheng WuPublished in: International journal of clinical practice (2022)
HUCWJCs can prevent the progression of osteoporosis by inhibiting oxidative stress, which may act by regulating osteoblasts fate through the MAPK signaling pathway.
Keyphrases
- signaling pathway
- umbilical cord
- induced apoptosis
- mesenchymal stem cells
- oxidative stress
- pi k akt
- postmenopausal women
- bone mineral density
- cell cycle arrest
- endothelial cells
- epithelial mesenchymal transition
- endoplasmic reticulum stress
- dna damage
- induced pluripotent stem cells
- bone marrow
- mouse model
- diabetic rats
- ischemia reperfusion injury
- cell death
- cell proliferation
- body composition
- heat stress