Genetic determinants of clinical phenotype in hypertrophic cardiomyopathy.

Lazar VelickiDjordje G JakovljevicAndrej PrevedenMiodrag GolubovicMarija BjelobrkAleksandra IlicSnezana StojsicFausto BarloccoMaria TafelmeierNduka OkwoseMilorad TesicPaul BrennanDejana PopovicArsen RisticGuy A MacGowanNenad FilipovicLars S MaierIacopo Olivotto

Published in: BMC cardiovascular disorders (2020)

Major findings of the present study corroborate the notion that MYH7 gene mutation patients are presented with more pronounced disease severity than those with MYBPC3.

Keyphrases

hypertrophic cardiomyopathy
left ventricular
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
heart failure
peritoneal dialysis
genome wide
gene expression
copy number
atrial fibrillation