Single-fraction prostate-specific membrane antigen positron emission tomography- and multiparametric magnetic resonance imaging-guided stereotactic body radiotherapy for prostate cancer local recurrences.
Felix EhretTheresa HofmannChristoph FürwegerMarkus KufeldMichael StaehlerAlexander MuacevicAlfred HaidenbergerPublished in: BJU international (2022)
While the available data for SBRT in the PCa local recurrence setting describe outcomes for fractionated irradiations, the findings of this first analysis of single-fraction, PSMA-PET- and mpMRI-guided focal SBRT are encouraging. Such treatment appears to be a safe, efficient, and time-saving therapy even in intensively pretreated patients. Recurrence-directed treatments can delay the use of ADT and could avoid prostate bed irradiation in selected patients.
Keyphrases
- chronic kidney disease
- end stage renal disease
- prostate cancer
- positron emission tomography
- magnetic resonance imaging
- computed tomography
- radiation therapy
- pet ct
- ejection fraction
- early stage
- newly diagnosed
- stem cells
- metabolic syndrome
- electronic health record
- type diabetes
- squamous cell carcinoma
- artificial intelligence
- benign prostatic hyperplasia
- magnetic resonance
- mesenchymal stem cells
- combination therapy
- free survival
- prognostic factors
- bone marrow
- patient reported