Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agents.

Sumanth KhadkeNayla AhmedNausheen AhmedRyan RattsShine RajuMolly GalloglyMarcos de LimaMuhammad Rizwan Sohail

Published in: Virology journal (2020)

Evidence regarding SARS-CoV-2 epidemiology and pathogenesis is rapidly evolving. A better understanding of the pathophysiology and immune system dysregulation associated with CRS and acute respiratory distress syndrome in severe COVID-19 is imperative to identify novel drug targets and other therapeutic interventions.

Keyphrases

sars cov
acute respiratory distress syndrome
extracorporeal membrane oxygenation
coronavirus disease
respiratory syndrome coronavirus
mechanical ventilation
risk factors
physical activity
early onset
drug induced