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Clinical utility of liquid biopsy for EGFR driver, T790M mutation and EGFR amplification in plasma in patients with acquired resistance to afatinib.

Yuko OyaJeffrey S WeberKazuhiro AsadaTetsuya OguriNaoki InuiSayako MorikawaKentaro ItoTomoki KimuraEiji KuniiTakashi MatsuiAkihito KuboTatsuo KatoTakashi AbeTakeshi TsudaToyoaki Hida
Published in: BMC cancer (2021)
The detection of EGFR-driver and T790M in plasma by cobas in patients treated with afatinib might be lower than with G/E in a real-world setting.
Keyphrases
  • epidermal growth factor receptor
  • small cell lung cancer
  • tyrosine kinase
  • advanced non small cell lung cancer
  • label free
  • ionic liquid
  • ultrasound guided
  • nucleic acid