Inhibiting the redox function of APE1 suppresses cervical cancer metastasis via disengagement of ZEB1 from E-cadherin in EMT.
Qing LiZhi-Wei ZhouWei DuanCheng-Yuan QianShu-Nan WangMeng-Sheng DengDan ZiJian-Min WangCheng-Yi MaoGuanbin SongDong WangKenneth D WestoverCheng-Xiong XuPublished in: Journal of experimental & clinical cancer research : CR (2021)
Our findings help to elucidate the role played by APE1 in cervical cancer metastasis and targeting APE1 redox function may be a novel strategy for inhibiting cervical cancer metastasis.