Transcriptome analysis reveals modulation of the STAT family in PEDV-infected IPEC-J2 cells.

Zhengzheng HuYuchen LiHeng DuJunxiao RenXianrui ZhengKejian WeiJian-Feng Liu

Published in: BMC genomics (2020)

Our transcriptomic analysis described the host genetic response to PEDV infection in detail in IPEC-J2 cells, and suggested that STAT transcription factors may serve as key regulators in the response to PEDV infection. These results further our understanding of the pathogenesis of PEDV.

Keyphrases

induced apoptosis
transcription factor
cell cycle arrest
cell proliferation
endoplasmic reticulum stress
gene expression
dna binding