Oxidative cascade cyclization of N -arylacrylamides with TMSN 3 .

An azido-radical-triggered cyclization of N -( o -cyanobiaryl)acrylamides with TMSN 3 via a C(sp 3 )-N/C(sp 2 )-C(sp 3 )/C(sp 2 )-N bond formation cascade is described. This reaction features mild conditions and high bond-forming efficiency, making it an efficient method for the construction of azide-substituted pyridophenanthridines.