TAS1R2 rs35874116 and TRPM5 rs886277 polymorphisms are not related with risk of obesity.

Gulsah Koc Ahu Soyocak Serap Andac-Ozturk

Published in: International journal of clinical practice (2021)

Although TAS1R2 and TRPM5 genes were associated with taste preferences in previous studies, we found out that TAS1R2 rs35874116 and TRPM5 rs886277 variants are not associated with obesity. The functional potency of the genetic variants within TAS1R2 and TRPM5 may be different between ethnic groups and this requires further investigations.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
type diabetes
weight gain
high fat diet induced
genome wide
copy number
adipose tissue
gene expression
dna methylation
physical activity
body mass index
transcription factor