Gα i -derived peptide binds the µ-opioid receptor.

Piotr KossońJolanta DyniewiczPiotr F J LipińskiJoanna MatalińskaAleksandra MisickaAndrzej J BojarskiStefan Mordalski

Published in: Pharmacological reports : PR (2023)

subunit is sufficient to stabilize the active conformation of the receptor. Our approach opens the possibility to investigate the GPCR-G protein interface with peptide modification.

Keyphrases

chronic pain
pain management
binding protein
crystal structure